4,6-Dimethoxy-2-(methylsulfonyl)pyrimidine
نویسندگان
چکیده
The asymmetric unit of the title compound, C(7)H(10)N(2)O(4)S, comprises of two independent mol-ecules (A and B) which differ in the orientation of the methyl-sulfonyl group [C-S-C-N = 157.98 (13)° in mol-ecule A and 6.09 (18)° in mol-ecule B]. In the crystal structure, mol-ecules of type A are linked into chains along the a axis by inter-molecular C-H⋯O hydrogen bonds. The B mol-ecules are linked to these chains by C-H⋯O hydrogen bonds.
منابع مشابه
4,6-Dimethoxy-2-(methylsulfanyl)pyrimidine
The title compound, C(7)H(10)N(2)O(2)S, is essentially planar [maximum deviation 0.018 (4) Å]. In the crystal, mol-ecules are linked into chains by C-H⋯N hydrogen bonds and the chains are arranged in layers parallel to the ab plane.
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In the title compound, C10H16N2O9S3, the pyrimidine ring of the 1,3-dimethyl barbituric acid moiety has an envelope conformation with the C atom carrying the methyl-sulfonyl and bis-(methyl-sulfon-yl)methyl substituents as the flap. The dihedral angle between mean plane of the pyrimidine ring and the S/C/S plane is 72.4 (3)°. In the crystal, mol-ecules are linked via C-H⋯O hydrogen bonds, formi...
متن کامل4,6-Dimethoxy-2-(methylsulfanyl)pyrimidine–4-hydroxybenzoic acid (1/1)
The base mol-ecule of the title co-crystal, C7H10N2O2S·C7H6O3, is essentially planar, with a maximum deviation of 0.0806 (14) Å for all non-H atoms. The acid mol-ecule is also nearly planar, with a dihedral angle of 8.12 (14)° between the benzene ring and the carb-oxy group. In the crystal, the acid mol-ecules form an inversion dimer through a pair of O-H⋯O hydrogen bonds with an R2(2)(8) ring ...
متن کامل4,6-Dimethoxy-2-(methylsulfanyl)pyrimidinium chloride
In the title compound, C(7)H(11)N(2)O(2)S(+)·Cl(-), the 4,6-dimeth-oxy-2-(methyl-sulfan-yl)pyrimidinium cation is essentially planar (r.m.s. deviation = 0.043 Å). In the crystal, the anions and cations are connected by inter-molecular N-H⋯Cl and C-H⋯Cl hydrogen bonds, forming a two-dimensional network parallel to (011). Adjacent networks are cross-linked via π-π inter-actions involving the pyri...
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A number of substituted-α,β-unsaturated carbonyl compounds (1a-i) were prepared by Claisen-Schmidt condensation of substituted acetophenone with selected araldehydes, which on cycloaddition with thiourea furnished 4,6-disubstituted pyrimidine-2-thiols (2a-i). Reaction of (2a-i) with ethyl chloroacetate followed by condensation with hydrazine hydrate yielded 2-[(4,6-disubstituted pyrimidine-2-yl...
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عنوان ژورنال:
دوره 66 شماره
صفحات -
تاریخ انتشار 2010